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DNA methylation induces ferroptosis in tumor cells by regulating GPX4, a key molecule in ferroptosis

This process is accompanied by the activation of NOD-like receptor thermal protein domain-associated protein 3(NLRP3) inflammatory vesicles and the formation of neutrophil extracellular trapping networks (NETs), which exacerbate corneal epithelial damage and persistent microbial infection

Elevated levels of these reducing agents have been linked to a range of issues, from diminished oxidative capacity and tissue damage to an unexpected surge in ROS [215]

The key caution

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