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These formulations encapsulate amphotericin B as the active pharmaceutical ingredient (API)

The increase in unscheduled glycolysis may lead to DNA damage at least partially by reducing the dNTP pool by O-GlcNAcylation of ribonucleotide reductase catalytic subunit M1(RRM1), which may subsequently cause adaptive DNA mutations to maintain cell survival [10]

However, biofouling, protein adsorption, and electrode degradation may compromise signal stability, often limiting the operational lifetime to approximately 7-14 days [33,34]

Matsubara Y, Kiyohara H, Teratani T, Mikami Y, Kanai T

The presence of methyl groups in DNA chains is necessary for the formation of chromosome structure and the regulation of gene transcription (Jorgensen and Ro, 2019