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Ann Surg (2002) 236(1):3742

However, patients have a 5-year survival rate of only approximately 60%, and sarcoma cells are highly resistant to chemotherapy

Fine-needle aspirates might not provide diagnostic cellular tissue, whereas excisional biopsies rarely meet the appropriate margins (5 cm in two fascial planes) as required in the case of FISS, thus increasing the morbidity and mortality risks associated with sarcoma invasion (Stone et al., 2020)