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NNMT directly regulates the detoxification of endogenous and exogenous drugs/xenobiotics by the formation of methylated metabolic products, such as 1-methyl nicotinamide (1-MNA), methylated pyridiniums, and methylated related analogs

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Now, published in Scientific Reports , Watowich and colleagues from the University of Texas Medical branch show that treating with 5-amino-1MQ improves grip strength to a greater degree than rigorous exercise in aged mice