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For the IPGTT, D-glucose was injected intraperitoneally (2 g/kgBW) into over-night fasted mice, and, subsequently, blood was taken from the tail vein at 5, 15, 30, 60, 90 and 120 min after glucose loading and blood glucose levels were measured by the Accu-Chek glucometer (Roche Diagnostics, Indianapolis, United States)

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