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Front Physiol 12:751374 Shaw AC, Goldstein DR, Montgomery RR (2013) Age-dependent dysregulation of innate immunity

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Finally, the gene-protein-reaction (GPR) associations were manually added to each reaction based on the enzyme subunit and isoenzyme information obtained from the biochemical databases

Therefore, the goal of studying SNP is a better understanding of inter-individual pharmacologic variation due to polymorphism of ABCB1, which may open a window for individualized therapy based on the patients ABC transporter genotype ( ABCB1 inhibitors Competitive inhibitors of ABCB1 are categorized into three generations of drugs based on pharmacodynamics characteristics ( Table 2 )