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While antioxidant therapy holds promise, careful consideration of its indications, dosage, and potential risks is crucial to avoid inadvertently compromising male reproductive health [8, 24]

The mismatch between oxidized miRNAs and proteins might be involved in the initiation of apoptosis, that eventually leads to the cell death (Wang et al., 2015

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Unlike GPx1GPx4, GPx5 does not contain selenocysteine but contains cysteine residues in the active site, and GPx5 does not exhibit typical dismutation activity toward substrates such as H 2 O 2 (Taylor et al