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It reduces inflammatory cell recruitment, contributes to hormonal regulation, interferes with chemokine-mediated lesion establishment, and modulates mitochondrial biogenesis in a context-dependent manner

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This encompasses factors include internalization, recycling, turnover rates, lysosomal degradation, and obligate mechanisms [26]

Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis identified the MAPK signaling pathway (hsa04010) as a key mechanism involving 33 critical proteins, including AKT1, TP53, TNF, EGFR, RELA, and MAPK1