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Meanwhile, the ratio of GSR to GPX4 at the protein level was decreased in the A2ARi-treated group compared with the control group (Figure 3I), indicating that the GSSG accumulation upon A2ARi treatment is caused likely by an impaired capacity to recycle GSSG back to GSH

Toward the rational control of transsulfuration

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doi:10.1016/j.placenta.2014.12.009 [doi] Krotulski AJ, Garibay N, Walther D, Walton SE, Mohr ALA, Logan BK, Baumann MH., Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid, 5F-MDMB-PICA, in male rats, Neuropharmacology

For this purpose, 50 mg/kg thiopental sodium via IP was administered to the rats, and after vestibulocochlear nerve tissues were removed from the animals, and oxidant (MDA) and antioxidant (tGSH, SOD, and CAT) parameters were studied in tissues