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Because increased body iron stores reduce iron absorption, hemochromatosis represents an inappropriately high rate of iron absorption relative to body iron stores

There is the increased pressure in the superior sagittal sinus presenting with the systemic arterial and venous thrombosis, severe brain and peripheral disturbances, cardiac dysfunction, lung congestion, kidney congestion, liver failure, portal and caval hypertension, aortal hypotension and hemorrhagic lesions in gastrointestinal tract, especially in the stomach and duodenum

In summary, the unique pharmacological characteristics of active substances in TCM compound formulas play important roles in protecting the intestinal barrier

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Dickson et al., 2010