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Therefore, the M1 phenotype mainly relies on compensatory glycolysis for rapid energy supply, and mitochondria still maintain part of their function to support the enhanced RET, resulting in the explosively generated ROS (80)

When the liver breaks down alcohol, it produces acetaldehyde, a toxic byproduct that requires massive amounts of glutathione to neutralize

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CA Cancer J Clin 68:730 Silva MM, Santos MR, Caroo G, Rocha R, Justino G, Mira L (2002) Structure-antioxidant activity relationships of flavonoids: a re-examination