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doi: 10.1158/1541-7786.MCR-16-0305 186 GrandeBMGerhardDSJiangAGrinerNBAbramsonJSAlexanderTBet al

Liver protein was precipitated and resuspended in ammonium bicarbonate containing internal standards

Dose-limiting toxicity has not been precisely defined in humans, yet practitioners should terminate infusions if severe dizziness, chest tightness, or abrupt blood-pressure drops occur, then reassess electrolyte status and acid-base balance before re- challenge

Subsequent handling and storage were conducted in a sterile environment to minimize microbial contamination during formulation and use