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64 : 259264 Akhand AA, Du J, Liu W, Hossain K, Miyata T, Nagase F, Kato M, Suzuki H and Nakashima I (2002) Redox-linked cell surface-oriented signaling for T-cell death

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However, UPR can also activate downstream apoptotic signaling pathways and promote apoptosis when the damage is persistent and severe or when the extent of the crosstalk network exceeds the resolution capacity of ER loading aberrations ( Figure 2 )

Addition of PPG reduced also intracellular hypotaurine levels: from 7.46 3.55 to 0.31 0.12 nmol/mg protein (control vs