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In SS, TGP helps regulate the Th1/Th2 balance and inhibits the STAT signaling pathway, thereby reducing glandular inflammation

nucleatum in various non-oral pathological tissues, such as DNA of these bacteria has been identified in colorectal cancer tissues, atherosclerotic plaques, and placental tissues (Cui et al., 2025

Genetics G6PD deficiency is transmitted in x-linked disorder pattern

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Acute attacks GI symptoms: severe abdominal pain, nausea, vomiting, constipation Neurological abnormalities: polyneuropathies (nonspecific pain, weakness/fatigue, paresthesia, paresis), seizures, respiratory paralysis Autonomic dysfunction: tachycardia, hypertension Psychiatric abnormalities: hallucinations, disorientation, anxiety, insomnia Red-purple urine Chronic symptoms Most patients remain asymptomatic between attacks