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J Pharmacol Exp Ther 2009, 328 (3) : 732739

The body has evolved intricate antioxidant defense mechanisms to mitigate the damage caused by free radicals

Antiestrogenic action Among the oncostatic effects of melatonin, antiestrogenic actions are instrumental, especially relevant in hormone-dependent tumors, such as breast, prostate, and ovarian cancer [49]

SCD1 expression is associated with poor prognosis in PDAC patients and can protect cancer cells from ferroptosis, indicating its antitumour potential [94]

Macroautophagy (autophagy hereafter) is a process of cellular self-digestion that involves the sequestration of cytoplasmic contents into a vesicle (the autophagosome) that fuses with the lysosome where it is degraded