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One study demonstrated that gluconeogenic intermediates, such as pyruvate, malate, and phosphoenolpyruvate (PEP), are neuroprotective against MPP + toxicity

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Combined with the role of IGF/IGF-1R in DRG and spinal cord, IGF/IGF-1R in different regions of the brain may play different roles in regulating pain, which also needs further research in the future

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Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a vital role in various bodily functions