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This co-transporter plays a role in transporting adenosine across the macula densa cell membrane, which is involved in the tubuloglomerular feedback mechanism that maintains volume homeostasis

Vanni VS, De Lorenzo R, Privitera L, Canti V, Vigan P, Rovere-Querini P

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The absence of OCTN3 in humans, along with functional differences in OCT1 between humans and rodents, suggests that there are differences in the physiological and metabolic characteristics of carnitine across species

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