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In 2011, carglumic acid became available as a substitute for N-acetylglutamate for N-acetylglutamate synthase deficiency

A special thanks for the long-term subsidy mechanism from the Ministry of Finance and the Ministry of Education of PRC (People's Republic of China) for BUCM (Beijing University of Chinese Medicine)

The supernatant obtained was neutralized using 1 M Na 2 HPO 4

*Correspondence: Shaneel Chandra [email protected] Chapman [email protected] This article was submitted to Neuroinfectious Diseases, a section of the journal Frontiers in Neurology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers