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doi: 10.1016/j.toxlet.2013.12.023 218 YangXWangXLiuDYuLXueBShiH

Research Applications Telomere Biology and Telomerase Research Epitalon serves as a research tool for investigating telomere dynamics and telomerase regulation: Telomerase Activity Studies: Investigation of telomerase reverse transcriptase (TERT) gene expression and enzyme activity modulation Telomere Length Analysis: Research on telomere elongation mechanisms and maintenance processes Cellular Senescence Research: Examination of replicative senescence pathways and senescence-associated markers Cell Cycle Regulation: Studies on proliferative capacity and cell division potential in various cell types Chromosome Stability Research: Investigation of telomere-mediated chromosome protection mechanisms Research protocols employ telomere restriction fragment (TRF) analysis, telomerase repeat amplification protocol (TRAP) assays, quantitative PCR for telomere length assessment, and fluorescence in situ hybridization (FISH) techniques

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It is not FDA-approved for human use, which affects its legal availability and can impact pricing due to limited sources

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