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Mitophagy is a double-edged sword that can promote cell survival and accelerate cell apoptosis, depending on physiological and pathological context ( Process of mitophagy In mammalian cells, under some stressful conditions, damaged mitochondria undergo membrane potential loss, isolation, or fission from the network, relying on DRP1 activity or autophagy machinery (Montava-Garriga and Ganley, 2020)

[DOI] [PubMed] [Google Scholar] 78.Hofhaus G., Weiss H., Leonard K

When exposed to bile acids, ME-3 survived for 24 hours without significant loss of live bacteria. Thus, Lactobacillus fermentum ME-3 can tolerate exposure to harsh acidity in the stomach as well as exposure to bile acids in the small intestine