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The mammalian target of rapamycin (mTOR), a key protein downstream of the phosphatidylinositol 3-kinase/protein kinase (PI3K/AKT) pathway, is closely associated with insulin metabolic dysfunction and exerts a substantial impact on the growth and proliferation of FGCs

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MiRNAs play pivotal roles in manifesting lethal phenotypes in cancer cells, including MDR, growth, differentiation, and metastasis among cancer stem cells, and miRNAs can also be used to regulate the abnormal function of target genes (129)