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The common features of these EBV-related autoimmune diseases are elevated plasma viral loads and levels of EBV-directed antibodies that result in decreased EBV-directed cell-mediated immunity, suggesting the presence of widespread lytic EBV infection in patients

Mechanistically, this effect was shown to be partially dependent on the ETC, and to restore mitochondrial protein import in a mutant yeast strain 15

There were no signs of inflammation, necrosis, or fibrosis

Polyamines: functions, metabolism, and role in human disease management