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Description

Petrosillo, G., Ruggiero, F

To test whether the GSH rhythm is controlled by the clock mechanism, we measured GSH in heads of arrhythmic clock mutants with loss of cyc ( cyc 01 ) or per ( per 01 ) function

It has been shown that the gmhA , hldE , rfaD , and waaC gene deletions encoding enzymes of the ADP-heptose synthesis pathway provoke a significant decrease in the intracellular pool of cysteine with a simultaneous increase in the total pool of reduced thiols