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High-fat meals might slow down the process, reducing efficacy

Iscience 28 , 113191 (2025)

176 LiaoY.LnnerdalB

In addition, reduced expression of insulin receptors (IRs) in synaptic membranes was accompanied by reduced learning/memory ( Streptozotocin infusion in rodents results in the development of sAD phenotypes, including hyperphosphorylation of tau proteins and loss of synaptic plasticity in the cerebral cortex (Figures 4, 5)