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Description

When the strains were incubated with CuSO 4 , as shown in Table 5, most of the investigated genes were apparently upregulated in gr compared with the wild type

Diabetes Care 42 , 12841289 (2019)

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BPC-157 , ,

Notably, several genes involved in glycolysis/gluconeogenesis (GNG) pathways, such as alcohol dehydrogenase 7 ( Adh7 ) and glucokinase ( Gck ), and genes related to antioxidant defense, including gamma-glutamyltransferase 6 ( Ggt6 ), glutathione S-transferase pi 3 ( Gstp3 ), and microsomal glutathione S-transferase 2 ( Mgst2 ), were downregulated in response to SIRT1 deletion (Fig