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For instance, pairing corticosteroids with vitamin D analogs (e.g., calcipotriol) enhances efficacy while reducing the required steroid dose and minimizing atrophy (Menter and Griffiths 2007)

Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values

Lancet 1 , 447451 (1977)

Endpoints frequently measured include the activity of alkaline phosphatase (ALP), an early marker of osteoblast differentiation, the expression of the master osteogenic transcription factor Runx2, and the deposition of a mineralized matrix, which can be visualized with Alizarin Red staining