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Mol Cell 76(5):838851.e5 Chen P, Li X, Zhang R, Liu S et al (2020) Combinative treatment of -elemene and cetuximab is sensitive to KRAS mutant colorectal cancer cells by inducing ferroptosis and inhibiting epithelial-mesenchymal transformation

Glutamate packaging In neurons, glutamate is packaged and stored in synaptic vesicles through specific vesicular glutamate transporters (VGLUT)

PARK7 (also known as protein deglycase DJ-1) has been suggested to be a negative regulator of PTEN 33 as well as a scavenger of ROS 34 and stabiliser of the transcription factor NRF2, a master regulator of the cellular response to redox stress 35

However, all AI disease involves similar mechanisms of immune dysregulation so these seemingly different diseases can be treated similarly by modulating some aspect of the immune response

Antioxidants are the cleanup crew