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3 Future direction Non-pharmacological treatments are still exploratory, with certain limitations and areas requiring further investigation

Iron accumulation/overload and Alzheimers disease risk factors in the precuneus region: A comprehensive narrative review

The effect of gut microbiota on drug metabolism

Many people will also experience cognitive difficulties such as problems with vision, memory, thinking, or reasoning, the development of mental illnesses such as depression, or general changes in behavior

High TPMT activity causes a universal increase in the different phosphorylated forms of the methylated metabolites, which have contrasting actions (Karim et al., 2013)