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Description

Multiple mechanisms mediate the pathogenesis and progression of OA, including ECM degradation, chondrocyte apoptosis, inflammatory responses, angiogenesis, and autophagy

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Mol Cell Neurosci 2003

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If neurological symptoms are present, treatment is more intensive: 1 mg on alternate days until no further improvement, then maintenance doses of 1 mg every 2 months

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For a deeper look at what GLP-1 approval actually required, Meto's clinical overview of GLP-1 drugs provides useful context as does our recent piece on Foundayo (orforglipron), the first oral GLP-1 to reach approval

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