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2006;291(1):F2236

Rada P, Rojo AI, Chowdhry S, McMahon M, Hayes JD, Cuadrado A

In comparing their blood samples with those of 45 demographically matched healthy people, the depressed patients' acetyl-L-carnitine blood levels were found to be substantially lower

Spread from injection site: Postmarketing reports indicate that the effects of Botox and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects In unapproved uses, including spasticity in children, and in approved indications, cases of spread of effect have been reported at doses comparable to those used to treat cervical dystonia and upper limb spasticity and at lower doses. -Botox boxed safety sheet Literature on use and benefits The Use of Botulinum Toxin for Treatment of Spasticity: A review of how Botox reduces spasticity but may have variable effects on voluntary movement, and considerations on improving efficacy

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