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All dogs were fed a low-carnitine diet in which amounts were determined based on maintaining a minimum initial starting body weight

[DOI] [PubMed] [Google Scholar] 121.Lentjes M.A., Welch A.A., Keogh R.H., Luben R.N., Khaw K.T

The protection of the hearing function could be explained by a combined antioxidant, neuroprotective and anti-inflammatory effect complemented by the enhancement of the action of an endogenous hearing protection mechanism via DA release from LOC efferents, the effector arm of a feedback loop, that attenuates the excitotoxic overactivation of the primary auditory neurons and their synapses with the IHCs

& Galvn, J

4 Therapeutic strategies targeting GPX4 for OA 4.1 Drugs directly Inhibiting lipid peroxidation or enhancing GPX4 activity 4.1.1 Classical ferroptosis inhibitors Ferrostatin-1(Fer-1) and Liproxstatin-1(Lip-1) are among the first identified and widely used specific small molecule inhibitors of ferroptosis