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Disclosure of interest: No disclosures E-Posters - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.02 - LIFE AFTER STROKE P2275 - ESOC25-1701 PREVALENCE OF RYANODINE ANTIBODIES IN STROKE PATIENTS WITH POST-STROKE FATIGUE (PSF): AN OBSERVATIONAL ANALYSIS Dr Karthika Pt, Vivek Nambiar 1 , Dr Sudheeran Kannoth 1 , Divyasree Chandran 1 Amrita Institute of Medical Sciences and Research Centre, Kochi, India Background and Aims: Post-stroke fatigue (PSF) is a debilitating sequela of stroke involving central and peripheral mechanisms

Studies evaluating caudatin in diseases such as liver damage and tumors have shown that it improves liver function indices and no significant adverse effects, suggesting that the drug is well tolerated (Wang et al., 2024

However, these findings do not yet form one complete and fully confirmed mechanism

[1] NNMT as a Metabolic Research Target Independent research groups have studied NNMT inhibition in diet-induced obese (DIO) mouse models

PMID 23301527