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271 utilized deep sequencing technology to characterize the EBV miRNA transcriptome in clinical NPC tissues

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This stress leads to suppression of forkhead box O1 (FoxO1) signaling and subsequent upregulation of thioredoxin interacting protein, inhibition of insulin and SOD-2 expression, re-expression of Neurog3, and -cell dedifferentiation and functional failure

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As ALS progresses, over 80% of patients develop difficulty swallowing (dysphagia), and many also experience increased metabolism, which raises their calorie needs by about 1520% more normal (Dupuis and Chio, 2023)