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In fact, GR and FK506 binding protein 5 (FKBP5) expression can be changed by the polyphenolic flavonoid icariin, which enhances GR stability and lessens GR sensitivity to GC in vivo (167)

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The drug stimulates the parathyroid hormone receptors in these bones and cartilage, which helps promote the growth of new bone cells

Cells in each group were cultured for 72 h for further study