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An open-label, single-arm pilot study involving 21 patients, evaluated the effect of 3,000 mg ALC daily on the intra-epidermal nerve fiber (IENF) density and mitochondrial DNA (mtDNA) copies/cell

66 In 53 sheltered dogs exhibiting high anxiety levels, eating food with nearly four times more tryptophan than standard food for six weeks reduced abnormal social behaviors associated with stress

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Consistent with this evidence, our immunohistochemical and molecular findings reported both a significant reduction in GAD67 enzyme expression and neuronal distribution, along with a striking reduction and altered morphology of PV+ INs in SMA SM CRTX mice

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