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23, 206210 10.3109/03009749409103062 [DOI] [PubMed] [Google Scholar] Nguyen D., Wagner-Britz L., Maia S., Steffen P., Wagner C., Kaestner L., et al

Conclusion: Utilizing advanced imaging methods, including MRI-PDFF and MRE, in a prospectively enrolled cohort of overweight and obese adults, the prevalence of cirrhosis was 4.5%

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The rates of any grade trAEs in Child-Pugh B patients were 40% (95%CI 34-47%), grade 3 or higher trAEs 12% (95%CI 6-23%)

62,109 These examples demonstrate that LPO and ferroptosis may be biologically irrelevant for APAP hepatotoxicity under normal conditions because endogenous defense mechanisms (such as the lipid-soluble antioxidant vitamin E and the iron chelator ferritin) effectively prevent excessive LPO