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doi: 10.1016/j.jep.2023.116604 9 KongLZhaoQJiangXHuJJiangQShengLet al

The mutations were found in all five exons of the gene, although the majority of the mutations are reported in exons 1 and 4 [Figure 12]

Even so, when studies are reviewed it is important to qualify that effects may be limited to specific populations and that safety and indications should be assessed individually