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Laboratory evaluation typically includes serum vitamin B12 levels, with values below 200 pg/mL generally indicating deficiency and levels between 200-300 pg/mL considered borderline, though laboratory reference ranges may vary

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Emerging evidence suggests that it functions as a central coordinator, ensuring that mitochondrial biogenesis is coupled with the regulation of mitochondrial morphology and the removal of damaged organelles, thereby maintaining a healthy and functional mitochondrial network