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In another small study involving 15 patients receiving hemodialysis (where blood is pumped out of the body to an artificial kidney machine), they were found to have gastrointestinal symptoms, including constipation (likely due to restrictions in their water intake required as part of their therapy), as well as carnitine deficiency

Making gradual changes to the diet may help identify which foods may trigger bloating and can be eliminated

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Citizen science platforms such as iNaturalist, Global Biodiversity Information Facility (GBIF), offer potential for populating distribution databases (see Supplementary Table 4 for citizen science-derived observation tallies across regions in eleven Southeast Asian countries)

However, most of these signaling pathways are either redundant or essential in healthy tissue making these types of target therapies challenging