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10.1016/S0021-9673(02)01971-4 109 LarreyD

Halogenated alkenes, hydroquinones, and quinones have been shown to form toxic metabolites via the formation of S-conjugates with GSH

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Taken together, these findings position AKT1 not only as a molecular hallmark of advanced lipedema but also as a promising therapeutic target that warrants further validation in preclinical models and pharmacological intervention studies