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Indirect comparison across trials suggests tirzepatide produces greater weight loss at currently approved doses

Overall, HCC was diagnosed in similar BCLC stages (0, A, B, C, and D in 19.5% and 18.8%, 26.9% and 26.6%, 35.4% and 35.3%, 14.9% and 15.9%, and 3.2% and 3.4%, respectively)

That matters for protocols where TB-500 needs to run higher (such as injury-focused work)

In this section, we will discuss how intestinal injury might affect the development of colorectal cancer, progression of myelodysplastic syndrome (MDS), and propagation of acute GVHD following allogeneic hematopoietic stem cell transplantation