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Only one trial [11] reported information regarding age and BMI (44.4 years and 23.88 kg/m 2 in mean, Table 1)

ACS Appl materials interfaces

FIGURE 3 Malondialdehyde is produced in vivo through both enzymatic and non-enzymatic oxidation, making it a widely monitored biomarker for oxidative stress across various diseases and particularly favored for characterizing oxidative stress in AD patients (57)

Figure 2 3.3 Antioxidant defense Lipid peroxidation can be countered by antioxidant systems, in which the cystine/glutamate-GSH-GPX4 is the main antioxidant pathway (29)