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Throughout this period, the presence of unstable lipid hydroperoxide (LOOH) results in the generation of various secondary products such as 4-HNE, propionaldehyde, hexenal, MDA, and acrolein [47]

Curcumin increases the expression of Nrf2, HO-1, and GPX4 in hepatocytes, inhibits the decline of mitochondrial membrane potential in hepatocytes, and all these changes could be reversed by ferroptosis inducer erastin, indicating that curcumin protects against Wilsons disease by inhibiting ferroptosis

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Indeed, the number of VOCs increased 1.2- to 1.8-fold (odorous VOCs: 2.0- to 3.7-fold), while the total amount increased 5.1- to 7.4-fold (7.7- to 13.6-fold) for bacteria grown in anaerobiosis when compared to those for bacteria grown in aerobiosis