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39 Emergence phenomena quickly resolve within minutes to hours of discontinuing treatment

Young CS, Hicks MR, Ermolova NV et al (2016) A Single CRISPR-Cas9 deletion strategy that targets the majority of DMD patients restores dystrophin function in hiPSC-derived muscle cells

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This effect may be attributed to a marked reduction in the expression of MuRF1 and atrogin-1, thereby delaying age-dependent dysregulation of muscle mass through the modulation of genes involved in muscle regeneration and catabolism ( Firmicutes / Bacteroides ratio, and enhances nutrient availability through the short-chain fatty acids produced by lactic acid (69)