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Likewise, the treatment of MSC-sEVs led to higher 24 h mouse survival rates and significant reductions in METs formation and liver injury compared to treatment with sEV-free concentrated medium, and the inflammatory infiltration and hyperemia of the liver tissue were decreased

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Ample evidence suggests that dysbiosis of gut microbiota is involved in renal disease [59, 60]

Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS