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While they offer unique advantages in stimulating robust immune responses, addressing their limitations, such as stability, purification challenges, and storage requirements, is crucial for maximizing their potential in global vaccination strategies [162]

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Despite lack of statistically significant outcome, 42.0% of patients treated with obexelimab (21/50) showed improvement compared to 28.6% on placebo (12/42) (P = 0.183)

N = 4 biologically independent samples per condition from 4 isolations

While the compound has shown efficacy in animal models, he notes that more research is needed to fully understand the risks and benefits for human use, especially over extended periods