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Loading phases utilizing higher frequency dosing (e.g., daily or every other day) for initial weeks followed by maintenance phases with reduced frequency have been described in some protocols, though the necessity and optimal duration of loading phases remain incompletely established

Proceedings of the 2nd Annual Pediatric Neuro-Oncology Basic and Translational Research Conference, Neuro-Oncology 190 TsuchidaS.SekineY.ShinehaR.NishihiraT.SatoK

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In the past two years, ferroptosis has been well investigated in DKD patients and animal models, but the specific mechanisms and therapeutic effects have not been fully revealed

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