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It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

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Figure 1 2.2.1 Early exploration and basic protection (1990s) In the 1990s, nutraceutical scientists first explored nanocarriers largely inspired by pharmaceutical advances

10.1016/j.freeradbiomed.2003.11.005 51 JongN