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Although the clinical correlates of the cellular pathology in bipolar disorder await better characterization, there is little doubt that documented pathohistological changes in key cortico-limbic areas and the white-matter tracts play an important role in the clinical manifestations of bipolar illness

Comment What has been described as granular degeneration can be seen in combination with other forms of liver damage (e.g., necrosis, hydropic degeneration, inflammation) (Huang et al

The results showed that patients who received tesofensine along with the diet experienced greater weight loss compared to those who only followed the diet and took the placebo