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Mol Biol Rep 48(9):65396550 Tibullo D, Li Volti G, Giallongo C, Grasso S, Tomassoni D, Anfuso CD, Lupo G, Amenta F, Avola R, Bramanti V (2017) Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential

It is difficult to replicate the complex environment faced by tumors and to exclude interference from multiple processes to precisely determine which modification is specifically regulated

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However, due to potential tissue-specific variations in miRNA levels associated with different histological subtypes of B-NHL, further studies with increased sample sizes and comparison of B-NHL tissues with the same histological classification are needed [162]

With the improved Lyso-IP method, we observed the enrichment of bands 2 and 4 and negligible amounts of bands 1 and 3 (Figure 2E)